欢迎来到专业的无忧考公务员网!

注册登陆 我要投稿
当前位置:无忧考公务员网>时事申论 >

MRI评价再发缓解型多发性硬化患者脑干横截面积及其临床意义

日期:2018-06-15 20:08:31 浏览次数:

  [摘要] 目的 探讨MRI评价再发缓解型多发性硬化患者脑干横截面积及其临床意义。 方法 临床选择2015年6月~2017年3月本院收治的再发缓解型多发性硬化患者15例为疾病组,另选取同期健康体检者15例为对照组,应用MRI检查两组的中脑面积、桥脑面积和延髓面积,评估疾病组与对照组的中脑面积、桥脑面积和延髓面积;采用美国国立卫生研究院卒中量表评估患者神经功能情况,评估疾病组脑组织不同萎缩程度的神经功能情况。 结果 疾病组的中脑面积、桥脑面积、延髓面积分别为(56.6±7.3)、(34.8±4.8)、(15.8±3.7)mm2显着低于对照组的(78.5±8.9)、(50.4±10.9)、(36.9±4.8)mm2,差异有统计学意义(P<0.05);疾病组的再发缓解型多发性硬化脑萎缩分级1 ~ 2级者的NIHSS评分(16.6±3.3)分显着低于3 ~ 4级的(28.5±8.9)分,差异有统计学意义(P<0.05)。 结论 MRI可用于评估再发缓解型多发性硬化患者的脑萎缩程度,进而提高对再发缓解型多发性硬化患者病情危险程度评估的准确性及实施针对性治疗措施的预见性。
  [关键词] 脑干横截面积;再发缓解型多发性硬化;MRI
  [中图分类号] R259 [文献标识码] A [文章编号] 2095-0616(2017)09-167-03
  Evaluation of cross sectional area of brain stem of relapsing remitting multiple sclerosis patients by MRI and its clinical significance
  YAN Dexing WEN Zhengqing
  Department of Medical Imaging, Shaoguan First People"s Hospital, Shaoguan 512000, China
  [Abstract] Objective To explore the evaluation of cross sectional area of brain stem of relapsing remitting multiple sclerosis patients by MRI

MRI评价再发缓解型多发性硬化患者脑干横截面积及其临床意义

and its clinical significance. Methods 15 cases of relapsing remitting multiple sclerosis patients cured in our hospital from June 2015 to March 2016 were selected as the disease group, and 15 cases of healthy physical examination during the same period were selected as control group. Midbrain area, pontine area and medulla area of the two groups were examined by MRI. Midbrain area, pontine area and medulla area of disease group and control group were evaluated. Neurological function was evaluated by stroke scale of National Institutes of health. Neurological function of brain tissue with different degrees of atrophy of disease group was evaluated. Results Midbrain area, pontine area, medulla area of disease group were (56.6±7.3), (34.8±4.8), (15.8±3.7)mm2, which were significantly less than those of control group with (78.5±8.9), (50.4±10.9), (36.9±4.8)mm2, and the differences were statistically significant (P<0.05). NIHSS scores of patients with relapsing remitting multiple sclerosis cerebral atrophy grade 1-2 was (16.6±3.3), which was significantly that of grade 3-4 with (28.5±8.9), and the difference was statistically significant (P<0.05). Conclusion MRI can be used to evaluate the degree of brain atrophy in patients with relapsing remitting multiple sclerosis, and then to improve the accuracy of the risk assessment of patients with relapsing remitting multiple sclerosis and the predictability of the implementation of targeted therapies.
  [Key words] Cross sectional area of brain stem; Relapsing remitting multiple sclerosis; MRI

声明:本网站尊重并保护知识产权,根据《信息网络传播权保护条例》,如果我们转载的作品侵犯了您的权利,请在一个月内通知我们,我们会及时删除。

Copyright©2024无忧考公务员网 www.51kaogwy.cn 版权所有